Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity linked to bortezomib, a proteasome inhibitor Utilized in the cure of various myeloma. Its synthesis or analyze is critical for making certain the purity and safety of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor in the synthesis of abiraterone acetate, a drug Utilized in the treatment of prostate most cancers by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-ten-1): A essential compound inside the synthesis of imatinib, a drug that targets precise forms of most cancers, like Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats various cancers such as breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates within the synthesis of gemcitabine, an anti-cancer drug. Their research is essential for optimizing the production procedure and guaranteeing superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is employed to deal 2-Butenoicacid with breast most cancers, and these intermediates are associated with its generation.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Utilized in the procedure of breast cancer. Various intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug helpful in dealing with cancers for instance ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Utilized in the procedure of colorectal cancer and little cell lung cancer.
three-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, that have several purposes, which includes antiviral Homes.
Vildagliptin Intermediates: Used in the manufacture of vildagliptin, CAS NO. 155405-80-4 an oral drug for style two diabetes that inhibits the enzyme DPP-four to manage blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is involved in the synthesis of various gluconic acid derivatives, which can be used in food stuff, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate 2: A precursor within the synthesis of canagliflozin, a medication utilised to deal with variety two diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).